What is an insulator?
Release time:
2023-11-23
Insulators, or edge elements, are special cis-acting elements. Its function is only to prevent the transmission of activation or suppression effects on chromatin, thus limiting the activity of chromatin to the structural domain. If an insulator is placed between the enhancer and the promoter, it prevents the enhancer from activating the promoter.
Insulators, or edge elements, are special cis-acting elements. Its function is only to prevent the transmission of activation or suppression effects on chromatin, thus limiting the activity of chromatin to the structural domain. If an insulator is placed between the enhancer and the promoter, it prevents the enhancer from activating the promoter. On the other hand, if an insulator is between the active gene and the heterochromatin, it can protect the gene from inactivation caused by the extension of heterochromatinization. Some insulators have only one function, and some have two functions.
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